August 12, 2019Age Science

Mitochondria - the energy factories of our bodies

Dr. Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he directs the Laboratory for Integrated and Systems Physiology (LISP).

Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focuses on understanding how diet, exercise and hormones control metabolism and change gene expression. He is considered to be one of the world experts in the field of mitochondrial health.

In this podcast you will learn about:

  • The importance of mitochondrial health and its impact on health span and longevity
  • The benefits of caloric restriction and exercise for health and life span?
  • What role do mitochondria play in our bodies?
  • How can we best improve mitochondrial activity?
  • What food should we eat to improve mitochondrial health?
  • Is stress always bad for us?


  • Aging is not a disease, it’s just a gradual slowdown and breakdown of physiology.
  • If you consume fewer calories, you're going to get those calories from your own body. And to get those calories from your own body, you really need to activate the mitochondria.
  • Upon aging, your mitochondria become less efficient, because they accumulate damage through the years. And that explains why there's less energy made.